Glycerin_guaiacolate
Category
Glycerin_guaiacolate Brand names, Glycerin_guaiacolate Analogs
Glycerin_guaiacolate Brand Names Mixture
No information avaliable
Glycerin_guaiacolate Chemical_Formula
C10H14O4
Glycerin_guaiacolate RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glycerin_guaiacolate fda sheet
Glycerin_guaiacolate msds (material safety sheet)
Glycerin_guaiacolate Synthesis Reference
No information avaliable
Glycerin_guaiacolate Molecular Weight
198.216 g/mol
Glycerin_guaiacolate Melting Point
78.5 oC
Glycerin_guaiacolate H2O Solubility
50 mg/mL
Glycerin_guaiacolate State
Solid
Glycerin_guaiacolate LogP
0.95
Glycerin_guaiacolate Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glycerin_guaiacolate Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glycerin_guaiacolate Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glycerin_guaiacolate Absorption
Rapidly absorbed from the GI tract
Glycerin_guaiacolate Toxicity
LD50 1510 mg/kg (rat, oral)
Glycerin_guaiacolate Patient Information
No information avaliable
Glycerin_guaiacolate Organisms Affected
Humans and other mammals
