Glyceryl_guiacolate
Category
Glyceryl_guiacolate Brand names, Glyceryl_guiacolate Analogs
Glyceryl_guiacolate Brand Names Mixture
No information avaliable
Glyceryl_guiacolate Chemical_Formula
C10H14O4
Glyceryl_guiacolate RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glyceryl_guiacolate fda sheet
Glyceryl_guiacolate msds (material safety sheet)
Glyceryl_guiacolate Synthesis Reference
No information avaliable
Glyceryl_guiacolate Molecular Weight
198.216 g/mol
Glyceryl_guiacolate Melting Point
78.5 oC
Glyceryl_guiacolate H2O Solubility
50 mg/mL
Glyceryl_guiacolate State
Solid
Glyceryl_guiacolate LogP
0.95
Glyceryl_guiacolate Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glyceryl_guiacolate Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glyceryl_guiacolate Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glyceryl_guiacolate Absorption
Rapidly absorbed from the GI tract
Glyceryl_guiacolate Toxicity
LD50 1510 mg/kg (rat, oral)
Glyceryl_guiacolate Patient Information
No information avaliable
Glyceryl_guiacolate Organisms Affected
Humans and other mammals
