Glyceryl_guaicolate
Category
Glyceryl_guaicolate Brand names, Glyceryl_guaicolate Analogs
Glyceryl_guaicolate Brand Names Mixture
No information avaliable
Glyceryl_guaicolate Chemical_Formula
C10H14O4
Glyceryl_guaicolate RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glyceryl_guaicolate fda sheet
Glyceryl_guaicolate msds (material safety sheet)
Glyceryl_guaicolate Synthesis Reference
No information avaliable
Glyceryl_guaicolate Molecular Weight
198.216 g/mol
Glyceryl_guaicolate Melting Point
78.5 oC
Glyceryl_guaicolate H2O Solubility
50 mg/mL
Glyceryl_guaicolate State
Solid
Glyceryl_guaicolate LogP
0.95
Glyceryl_guaicolate Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glyceryl_guaicolate Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glyceryl_guaicolate Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glyceryl_guaicolate Absorption
Rapidly absorbed from the GI tract
Glyceryl_guaicolate Toxicity
LD50 1510 mg/kg (rat, oral)
Glyceryl_guaicolate Patient Information
No information avaliable
Glyceryl_guaicolate Organisms Affected
Humans and other mammals