Guaia-rom
Category
Guaia-rom Brand names, Guaia-rom Analogs
Guaia-rom Brand Names Mixture
No information avaliable
Guaia-rom Chemical_Formula
C10H14O4
Guaia-rom RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaia-rom fda sheet
Guaia-rom msds (material safety sheet)
Guaia-rom Synthesis Reference
No information avaliable
Guaia-rom Molecular Weight
198.216 g/mol
Guaia-rom Melting Point
78.5 oC
Guaia-rom H2O Solubility
50 mg/mL
Guaia-rom State
Solid
Guaia-rom LogP
0.95
Guaia-rom Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaia-rom Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaia-rom Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaia-rom Absorption
Rapidly absorbed from the GI tract
Guaia-rom Toxicity
LD50 1510 mg/kg (rat, oral)
Guaia-rom Patient Information
No information avaliable
Guaia-rom Organisms Affected
Humans and other mammals
