Guaiacurane
Category
Guaiacurane Brand names, Guaiacurane Analogs
Guaiacurane Brand Names Mixture
No information avaliable
Guaiacurane Chemical_Formula
C10H14O4
Guaiacurane RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiacurane fda sheet
Guaiacurane msds (material safety sheet)
Guaiacurane Synthesis Reference
No information avaliable
Guaiacurane Molecular Weight
198.216 g/mol
Guaiacurane Melting Point
78.5 oC
Guaiacurane H2O Solubility
50 mg/mL
Guaiacurane State
Solid
Guaiacurane LogP
0.95
Guaiacurane Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiacurane Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiacurane Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiacurane Absorption
Rapidly absorbed from the GI tract
Guaiacurane Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiacurane Patient Information
No information avaliable
Guaiacurane Organisms Affected
Humans and other mammals