Guiaphenesin
Category
Guiaphenesin Brand names, Guiaphenesin Analogs
Guiaphenesin Brand Names Mixture
No information avaliable
Guiaphenesin Chemical_Formula
C10H14O4
Guiaphenesin RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guiaphenesin fda sheet
Guiaphenesin msds (material safety sheet)
Guiaphenesin Synthesis Reference
No information avaliable
Guiaphenesin Molecular Weight
198.216 g/mol
Guiaphenesin Melting Point
78.5 oC
Guiaphenesin H2O Solubility
50 mg/mL
Guiaphenesin State
Solid
Guiaphenesin LogP
0.95
Guiaphenesin Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guiaphenesin Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guiaphenesin Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guiaphenesin Absorption
Rapidly absorbed from the GI tract
Guiaphenesin Toxicity
LD50 1510 mg/kg (rat, oral)
Guiaphenesin Patient Information
No information avaliable
Guiaphenesin Organisms Affected
Humans and other mammals
