Guajacuran
Category
Guajacuran Brand names, Guajacuran Analogs
Guajacuran Brand Names Mixture
No information avaliable
Guajacuran Chemical_Formula
C10H14O4
Guajacuran RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guajacuran fda sheet
Guajacuran msds (material safety sheet)
Guajacuran Synthesis Reference
No information avaliable
Guajacuran Molecular Weight
198.216 g/mol
Guajacuran Melting Point
78.5 oC
Guajacuran H2O Solubility
50 mg/mL
Guajacuran State
Solid
Guajacuran LogP
0.95
Guajacuran Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guajacuran Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guajacuran Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guajacuran Absorption
Rapidly absorbed from the GI tract
Guajacuran Toxicity
LD50 1510 mg/kg (rat, oral)
Guajacuran Patient Information
No information avaliable
Guajacuran Organisms Affected
Humans and other mammals