Reduton
Category
Reduton Brand names, Reduton Analogs
Reduton Brand Names Mixture
No information avaliable
Reduton Chemical_Formula
C10H14O4
Reduton RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Reduton fda sheet
Reduton msds (material safety sheet)
Reduton Synthesis Reference
No information avaliable
Reduton Molecular Weight
198.216 g/mol
Reduton Melting Point
78.5 oC
Reduton H2O Solubility
50 mg/mL
Reduton State
Solid
Reduton LogP
0.95
Reduton Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Reduton Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Reduton Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Reduton Absorption
Rapidly absorbed from the GI tract
Reduton Toxicity
LD50 1510 mg/kg (rat, oral)
Reduton Patient Information
No information avaliable
Reduton Organisms Affected
Humans and other mammals