Methoxypropanediol
Category
Methoxypropanediol Brand names, Methoxypropanediol Analogs
Methoxypropanediol Brand Names Mixture
No information avaliable
Methoxypropanediol Chemical_Formula
C10H14O4
Methoxypropanediol RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Methoxypropanediol fda sheet
Methoxypropanediol msds (material safety sheet)
Methoxypropanediol Synthesis Reference
No information avaliable
Methoxypropanediol Molecular Weight
198.216 g/mol
Methoxypropanediol Melting Point
78.5 oC
Methoxypropanediol H2O Solubility
50 mg/mL
Methoxypropanediol State
Solid
Methoxypropanediol LogP
0.95
Methoxypropanediol Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Methoxypropanediol Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Methoxypropanediol Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Methoxypropanediol Absorption
Rapidly absorbed from the GI tract
Methoxypropanediol Toxicity
LD50 1510 mg/kg (rat, oral)
Methoxypropanediol Patient Information
No information avaliable
Methoxypropanediol Organisms Affected
Humans and other mammals
