Amphozone

Category

Amphozone




Useful info

Amphozone Brand names, Amphozone Analogs

Amphozone Brand Names Mixture

  • No information avaliable

    • Amphozone Chemical_Formula

    C47H73NO17

    Amphozone RX_link

    http://www.rxlist.com/cgi/generic2/amphoter.htm

    Amphozone fda sheet

    Amphozone FDA

    Amphozone msds (material safety sheet)

    Amphozone MSDS

    Amphozone Synthesis Reference

    No information avaliable

    Amphozone Molecular Weight

    924.079 g/mol

    Amphozone Melting Point

    170.0 oC

    Amphozone H2O Solubility

    750 mg/L

    Amphozone State

    Solid

    Amphozone LogP

    0.947

    Amphozone Dosage Forms

    Slow intravenous-infusion

    Amphozone Indication

    Used to treat potentially life threatening fungal infections.

    Amphozone Pharmacology

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

    Amphozone Absorption

    Bioavailability is 100% for intravenous infusion.

    Amphozone Toxicity

    Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

    Amphozone Patient Information

    No information avaliable

    Amphozone Organisms Affected

    Various Fungus Species