Fungizone Intravenous
Category
Fungizone Intravenous Brand names, Fungizone Intravenous Analogs
Fungizone Intravenous Brand Names Mixture
Fungizone Intravenous Chemical_Formula
C47H73NO17
Fungizone Intravenous RX_link
http://www.rxlist.com/cgi/generic2/amphoter.htm
Fungizone Intravenous fda sheet
Fungizone Intravenous msds (material safety sheet)
Fungizone Intravenous Synthesis Reference
No information avaliable
Fungizone Intravenous Molecular Weight
924.079 g/mol
Fungizone Intravenous Melting Point
170.0 oC
Fungizone Intravenous H2O Solubility
750 mg/L
Fungizone Intravenous State
Solid
Fungizone Intravenous LogP
0.947
Fungizone Intravenous Dosage Forms
Slow intravenous-infusion
Fungizone Intravenous Indication
Used to treat potentially life threatening fungal infections.
Fungizone Intravenous Pharmacology
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.
Fungizone Intravenous Absorption
Bioavailability is 100% for intravenous infusion.
Fungizone Intravenous side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.
Fungizone Intravenous Patient Information
No information avaliable
Fungizone Intravenous Organisms Affected
Various Fungus Species
