Ampho-Moronal

Ampho-Moronal Brand names, Ampho-Moronal Analogs

Ampho-Moronal Brand Names Mixture

No information avaliable

Ampho-Moronal Chemical_Formula

C₄₇H₇₃NO₁₇

Ampho-Moronal RX_link

http://www.rxlist.com/cgi/generic2/amphoter.htm

Ampho-Moronal fda sheet

Ampho-Moronal FDA

Ampho-Moronal msds (material safety sheet)

Ampho-Moronal MSDS

Ampho-Moronal Synthesis Reference

No information avaliable

Ampho-Moronal Molecular Weight

924.079 g/mol

Ampho-Moronal Melting Point

170.0 ^oC

Ampho-Moronal H₂O Solubility

750 mg/L

Ampho-Moronal State

Solid

Ampho-Moronal LogP

0.947

Ampho-Moronal Dosage Forms

Slow intravenous-infusion

Ampho-Moronal Indication

Used to treat potentially life threatening fungal infections.

Ampho-Moronal Pharmacology

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Ampho-Moronal Absorption

Bioavailability is 100% for intravenous infusion.

Ampho-Moronal side effects and Toxicity

Oral, rat: LD₅₀ = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

Ampho-Moronal Patient Information