Abelcet

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Abelcet




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Abelcet Brand names, Abelcet Analogs

Abelcet Brand Names Mixture

  • No information avaliable

    • Abelcet Chemical_Formula

    C47H73NO17

    Abelcet RX_link

    http://www.rxlist.com/cgi/generic2/amphoter.htm

    Abelcet fda sheet

    Abelcet FDA

    Abelcet msds (material safety sheet)

    Abelcet MSDS

    Abelcet Synthesis Reference

    No information avaliable

    Abelcet Molecular Weight

    924.079 g/mol

    Abelcet Melting Point

    170.0 oC

    Abelcet H2O Solubility

    750 mg/L

    Abelcet State

    Solid

    Abelcet LogP

    0.947

    Abelcet Dosage Forms

    Slow intravenous-infusion

    Abelcet Indication

    Used to treat potentially life threatening fungal infections.

    Abelcet Pharmacology

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

    Abelcet Absorption

    Bioavailability is 100% for intravenous infusion.

    Abelcet Toxicity

    Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

    Abelcet Patient Information

    No information avaliable

    Abelcet Organisms Affected

    Various Fungus Species