Halizon

Category

Halizon




Useful info

Halizon Brand names, Halizon Analogs

Halizon Brand Names Mixture

  • No information avaliable

    • Halizon Chemical_Formula

    C47H73NO17

    Halizon RX_link

    http://www.rxlist.com/cgi/generic2/amphoter.htm

    Halizon fda sheet

    Halizon FDA

    Halizon msds (material safety sheet)

    Halizon MSDS

    Halizon Synthesis Reference

    No information avaliable

    Halizon Molecular Weight

    924.079 g/mol

    Halizon Melting Point

    170.0 oC

    Halizon H2O Solubility

    750 mg/L

    Halizon State

    Solid

    Halizon LogP

    0.947

    Halizon Dosage Forms

    Slow intravenous-infusion

    Halizon Indication

    Used to treat potentially life threatening fungal infections.

    Halizon Pharmacology

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

    Halizon Absorption

    Bioavailability is 100% for intravenous infusion.

    Halizon Toxicity

    Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

    Halizon Patient Information

    No information avaliable

    Halizon Organisms Affected

    Various Fungus Species