Amphotec

Category

Amphotec




Useful info

Amphotec Brand names, Amphotec Analogs

Amphotec Brand Names Mixture

  • No information avaliable

    • Amphotec Chemical_Formula

    C47H73NO17

    Amphotec RX_link

    http://www.rxlist.com/cgi/generic2/amphoter.htm

    Amphotec fda sheet

    Amphotec FDA

    Amphotec msds (material safety sheet)

    Amphotec MSDS

    Amphotec Synthesis Reference

    No information avaliable

    Amphotec Molecular Weight

    924.079 g/mol

    Amphotec Melting Point

    170.0 oC

    Amphotec H2O Solubility

    750 mg/L

    Amphotec State

    Solid

    Amphotec LogP

    0.947

    Amphotec Dosage Forms

    Slow intravenous-infusion

    Amphotec Indication

    Used to treat potentially life threatening fungal infections.

    Amphotec Pharmacology

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

    Amphotec Absorption

    Bioavailability is 100% for intravenous infusion.

    Amphotec Toxicity

    Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

    Amphotec Patient Information

    No information avaliable

    Amphotec Organisms Affected

    Various Fungus Species