Fungisone

Category

Fungisone




Useful info

Fungisone Brand names, Fungisone Analogs

Fungisone Brand Names Mixture

  • No information avaliable

    • Fungisone Chemical_Formula

    C47H73NO17

    Fungisone RX_link

    http://www.rxlist.com/cgi/generic2/amphoter.htm

    Fungisone fda sheet

    Fungisone FDA

    Fungisone msds (material safety sheet)

    Fungisone MSDS

    Fungisone Synthesis Reference

    No information avaliable

    Fungisone Molecular Weight

    924.079 g/mol

    Fungisone Melting Point

    170.0 oC

    Fungisone H2O Solubility

    750 mg/L

    Fungisone State

    Solid

    Fungisone LogP

    0.947

    Fungisone Dosage Forms

    Slow intravenous-infusion

    Fungisone Indication

    Used to treat potentially life threatening fungal infections.

    Fungisone Pharmacology

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

    Fungisone Absorption

    Bioavailability is 100% for intravenous infusion.

    Fungisone Toxicity

    Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

    Fungisone Patient Information

    No information avaliable

    Fungisone Organisms Affected

    Various Fungus Species