Fungizone

Category

Fungizone




Useful info

Fungizone Brand names, Fungizone Analogs

Fungizone Brand Names Mixture

  • No information avaliable

    • Fungizone Chemical_Formula

    C47H73NO17

    Fungizone RX_link

    http://www.rxlist.com/cgi/generic2/amphoter.htm

    Fungizone fda sheet

    Fungizone FDA

    Fungizone msds (material safety sheet)

    Fungizone MSDS

    Fungizone Synthesis Reference

    No information avaliable

    Fungizone Molecular Weight

    924.079 g/mol

    Fungizone Melting Point

    170.0 oC

    Fungizone H2O Solubility

    750 mg/L

    Fungizone State

    Solid

    Fungizone LogP

    0.947

    Fungizone Dosage Forms

    Slow intravenous-infusion

    Fungizone Indication

    Used to treat potentially life threatening fungal infections.

    Fungizone Pharmacology

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

    Fungizone Absorption

    Bioavailability is 100% for intravenous infusion.

    Fungizone Toxicity

    Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

    Fungizone Patient Information

    No information avaliable

    Fungizone Organisms Affected

    Various Fungus Species