Amphocin

Category

Amphocin




Useful info

Amphocin Brand names, Amphocin Analogs

Amphocin Brand Names Mixture

  • No information avaliable

    • Amphocin Chemical_Formula

    C47H73NO17

    Amphocin RX_link

    http://www.rxlist.com/cgi/generic2/amphoter.htm

    Amphocin fda sheet

    Amphocin FDA

    Amphocin msds (material safety sheet)

    Amphocin MSDS

    Amphocin Synthesis Reference

    No information avaliable

    Amphocin Molecular Weight

    924.079 g/mol

    Amphocin Melting Point

    170.0 oC

    Amphocin H2O Solubility

    750 mg/L

    Amphocin State

    Solid

    Amphocin LogP

    0.947

    Amphocin Dosage Forms

    Slow intravenous-infusion

    Amphocin Indication

    Used to treat potentially life threatening fungal infections.

    Amphocin Pharmacology

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

    Amphocin Absorption

    Bioavailability is 100% for intravenous infusion.

    Amphocin Toxicity

    Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

    Amphocin Patient Information

    No information avaliable

    Amphocin Organisms Affected

    Various Fungus Species