Amphocin

Amphocin Brand names, Amphocin Analogs

Amphocin Brand Names Mixture

No information avaliable

Amphocin Chemical_Formula

C₄₇H₇₃NO₁₇

Amphocin RX_link

http://www.rxlist.com/cgi/generic2/amphoter.htm

Amphocin fda sheet

Amphocin FDA

Amphocin msds (material safety sheet)

Amphocin MSDS

Amphocin Synthesis Reference

No information avaliable

Amphocin Molecular Weight

924.079 g/mol

Amphocin Melting Point

170.0 ^oC

Amphocin H₂O Solubility

750 mg/L

Amphocin State

Solid

Amphocin LogP

0.947

Amphocin Dosage Forms

Slow intravenous-infusion

Amphocin Indication

Used to treat potentially life threatening fungal infections.

Amphocin Pharmacology

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Amphocin Absorption

Bioavailability is 100% for intravenous infusion.

Amphocin side effects and Toxicity

Oral, rat: LD₅₀ = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

Amphocin Patient Information