Fungilin

Category

Fungilin




Useful info

Fungilin Brand names, Fungilin Analogs

Fungilin Brand Names Mixture

  • No information avaliable

    • Fungilin Chemical_Formula

    C47H73NO17

    Fungilin RX_link

    http://www.rxlist.com/cgi/generic2/amphoter.htm

    Fungilin fda sheet

    Fungilin FDA

    Fungilin msds (material safety sheet)

    Fungilin MSDS

    Fungilin Synthesis Reference

    No information avaliable

    Fungilin Molecular Weight

    924.079 g/mol

    Fungilin Melting Point

    170.0 oC

    Fungilin H2O Solubility

    750 mg/L

    Fungilin State

    Solid

    Fungilin LogP

    0.947

    Fungilin Dosage Forms

    Slow intravenous-infusion

    Fungilin Indication

    Used to treat potentially life threatening fungal infections.

    Fungilin Pharmacology

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

    Fungilin Absorption

    Bioavailability is 100% for intravenous infusion.

    Fungilin Toxicity

    Oral, rat: LD50 = >5 gm/kg. Amphotericin B overdoses can result in cardio-respiratory arrest.

    Fungilin Patient Information

    No information avaliable

    Fungilin Organisms Affected

    Various Fungus Species