Thioridazine
Brand names,
Thioridazine
Analogs
Thioridazine
Brand Names Mixture
Thioridazine
Chemical_Formula
C21H26N2S2
Thioridazine
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Thioridazine
fda sheet
Thioridazine
msds (material safety sheet)
Thioridazine
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Thioridazine
Molecular Weight
370.577 g/mol
Thioridazine
Melting Point
73 oC
Thioridazine
H2O Solubility
0.0336 mg/L
Thioridazine
State
Solid
Thioridazine
LogP
6.552
Thioridazine
Dosage Forms
Suspension; Tablet
Thioridazine
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Thioridazine
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Thioridazine
Absorption
60%
Thioridazine
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Thioridazine
Patient Information
Thioridazine
Organisms Affected
Humans and other mammals