Thioridazine Hcl
Brand names,
Thioridazine Hcl
Analogs
Thioridazine Hcl
Brand Names Mixture
Thioridazine Hcl
Chemical_Formula
C21H26N2S2
Thioridazine Hcl
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Thioridazine Hcl
fda sheet
Thioridazine Hcl
msds (material safety sheet)
Thioridazine Hcl
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Thioridazine Hcl
Molecular Weight
370.577 g/mol
Thioridazine Hcl
Melting Point
73 oC
Thioridazine Hcl
H2O Solubility
0.0336 mg/L
Thioridazine Hcl
State
Solid
Thioridazine Hcl
LogP
6.552
Thioridazine Hcl
Dosage Forms
Suspension; Tablet
Thioridazine Hcl
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Thioridazine Hcl
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Thioridazine Hcl
Absorption
60%
Thioridazine Hcl
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Thioridazine Hcl
Patient Information
Thioridazine Hcl
Organisms Affected
Humans and other mammals