Thioridazin
Brand names,
Thioridazin
Analogs
Thioridazin
Brand Names Mixture
Thioridazin
Chemical_Formula
C21H26N2S2
Thioridazin
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Thioridazin
fda sheet
Thioridazin
msds (material safety sheet)
Thioridazin
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Thioridazin
Molecular Weight
370.577 g/mol
Thioridazin
Melting Point
73 oC
Thioridazin
H2O Solubility
0.0336 mg/L
Thioridazin
State
Solid
Thioridazin
LogP
6.552
Thioridazin
Dosage Forms
Suspension; Tablet
Thioridazin
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Thioridazin
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Thioridazin
Absorption
60%
Thioridazin
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Thioridazin
Patient Information
Thioridazin
Organisms Affected
Humans and other mammals