Meleril
Brand names,
Meleril
Analogs
Meleril
Brand Names Mixture
Meleril
Chemical_Formula
C21H26N2S2
Meleril
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Meleril
fda sheet
Meleril
msds (material safety sheet)
Meleril
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Meleril
Molecular Weight
370.577 g/mol
Meleril
Melting Point
73 oC
Meleril
H2O Solubility
0.0336 mg/L
Meleril
State
Solid
Meleril
LogP
6.552
Meleril
Dosage Forms
Suspension; Tablet
Meleril
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Meleril
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Meleril
Absorption
60%
Meleril
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Meleril
Patient Information
Meleril
Organisms Affected
Humans and other mammals