Melleril
Brand names,
Melleril
Analogs
Melleril
Brand Names Mixture
Melleril
Chemical_Formula
C21H26N2S2
Melleril
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Melleril
fda sheet
Melleril
msds (material safety sheet)
Melleril
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Melleril
Molecular Weight
370.577 g/mol
Melleril
Melting Point
73 oC
Melleril
H2O Solubility
0.0336 mg/L
Melleril
State
Solid
Melleril
LogP
6.552
Melleril
Dosage Forms
Suspension; Tablet
Melleril
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Melleril
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Melleril
Absorption
60%
Melleril
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Melleril
Patient Information
Melleril
Organisms Affected
Humans and other mammals