Metlaril
Brand names,
Metlaril
Analogs
Metlaril
Brand Names Mixture
Metlaril
Chemical_Formula
C21H26N2S2
Metlaril
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Metlaril
fda sheet
Metlaril
msds (material safety sheet)
Metlaril
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Metlaril
Molecular Weight
370.577 g/mol
Metlaril
Melting Point
73 oC
Metlaril
H2O Solubility
0.0336 mg/L
Metlaril
State
Solid
Metlaril
LogP
6.552
Metlaril
Dosage Forms
Suspension; Tablet
Metlaril
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Metlaril
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Metlaril
Absorption
60%
Metlaril
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Metlaril
Patient Information
Metlaril
Organisms Affected
Humans and other mammals