Thoridazine Hydrochloride
Brand names,
Thoridazine Hydrochloride
Analogs
Thoridazine Hydrochloride
Brand Names Mixture
Thoridazine Hydrochloride
Chemical_Formula
C21H26N2S2
Thoridazine Hydrochloride
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Thoridazine Hydrochloride
fda sheet
Thoridazine Hydrochloride
msds (material safety sheet)
Thoridazine Hydrochloride
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Thoridazine Hydrochloride
Molecular Weight
370.577 g/mol
Thoridazine Hydrochloride
Melting Point
73 oC
Thoridazine Hydrochloride
H2O Solubility
0.0336 mg/L
Thoridazine Hydrochloride
State
Solid
Thoridazine Hydrochloride
LogP
6.552
Thoridazine Hydrochloride
Dosage Forms
Suspension; Tablet
Thoridazine Hydrochloride
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Thoridazine Hydrochloride
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Thoridazine Hydrochloride
Absorption
60%
Thoridazine Hydrochloride
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Thoridazine Hydrochloride
Patient Information
Thoridazine Hydrochloride
Organisms Affected
Humans and other mammals