Thioridazine Hydrochloride [Jan]
Brand names,
Thioridazine Hydrochloride [Jan]
Analogs
Thioridazine Hydrochloride [Jan]
Brand Names Mixture
Thioridazine Hydrochloride [Jan]
Chemical_Formula
C21H26N2S2
Thioridazine Hydrochloride [Jan]
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Thioridazine Hydrochloride [Jan]
fda sheet
Thioridazine Hydrochloride [Jan]
msds (material safety sheet)
Thioridazine Hydrochloride [Jan]
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Thioridazine Hydrochloride [Jan]
Molecular Weight
370.577 g/mol
Thioridazine Hydrochloride [Jan]
Melting Point
73 oC
Thioridazine Hydrochloride [Jan]
H2O Solubility
0.0336 mg/L
Thioridazine Hydrochloride [Jan]
State
Solid
Thioridazine Hydrochloride [Jan]
LogP
6.552
Thioridazine Hydrochloride [Jan]
Dosage Forms
Suspension; Tablet
Thioridazine Hydrochloride [Jan]
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Thioridazine Hydrochloride [Jan]
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Thioridazine Hydrochloride [Jan]
Absorption
60%
Thioridazine Hydrochloride [Jan]
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Thioridazine Hydrochloride [Jan]
Patient Information
Thioridazine Hydrochloride [Jan]
Organisms Affected
Humans and other mammals