Mellarit
Brand names,
Mellarit
Analogs
Mellarit
Brand Names Mixture
Mellarit
Chemical_Formula
C21H26N2S2
Mellarit
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Mellarit
fda sheet
Mellarit
msds (material safety sheet)
Mellarit
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Mellarit
Molecular Weight
370.577 g/mol
Mellarit
Melting Point
73 oC
Mellarit
H2O Solubility
0.0336 mg/L
Mellarit
State
Solid
Mellarit
LogP
6.552
Mellarit
Dosage Forms
Suspension; Tablet
Mellarit
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Mellarit
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Mellarit
Absorption
60%
Mellarit
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Mellarit
Patient Information
Mellarit
Organisms Affected
Humans and other mammals