Tioridazin
Brand names,
Tioridazin
Analogs
Tioridazin
Brand Names Mixture
Tioridazin
Chemical_Formula
C21H26N2S2
Tioridazin
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Tioridazin
fda sheet
Tioridazin
msds (material safety sheet)
Tioridazin
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Tioridazin
Molecular Weight
370.577 g/mol
Tioridazin
Melting Point
73 oC
Tioridazin
H2O Solubility
0.0336 mg/L
Tioridazin
State
Solid
Tioridazin
LogP
6.552
Tioridazin
Dosage Forms
Suspension; Tablet
Tioridazin
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Tioridazin
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Tioridazin
Absorption
60%
Tioridazin
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Tioridazin
Patient Information
Tioridazin
Organisms Affected
Humans and other mammals