Usaf Sz-B
Brand names,
Usaf Sz-B
Analogs
Usaf Sz-B
Brand Names Mixture
Usaf Sz-B
Chemical_Formula
C21H26N2S2
Usaf Sz-B
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Usaf Sz-B
fda sheet
Usaf Sz-B
msds (material safety sheet)
Usaf Sz-B
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Usaf Sz-B
Molecular Weight
370.577 g/mol
Usaf Sz-B
Melting Point
73 oC
Usaf Sz-B
H2O Solubility
0.0336 mg/L
Usaf Sz-B
State
Solid
Usaf Sz-B
LogP
6.552
Usaf Sz-B
Dosage Forms
Suspension; Tablet
Usaf Sz-B
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Usaf Sz-B
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Usaf Sz-B
Absorption
60%
Usaf Sz-B
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Usaf Sz-B
Patient Information
Usaf Sz-B
Organisms Affected
Humans and other mammals