Aldazine
Brand names,
Aldazine
Analogs
Aldazine
Brand Names Mixture
Aldazine
Chemical_Formula
C21H26N2S2
Aldazine
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Aldazine
fda sheet
Aldazine
msds (material safety sheet)
Aldazine
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Aldazine
Molecular Weight
370.577 g/mol
Aldazine
Melting Point
73 oC
Aldazine
H2O Solubility
0.0336 mg/L
Aldazine
State
Solid
Aldazine
LogP
6.552
Aldazine
Dosage Forms
Suspension; Tablet
Aldazine
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Aldazine
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Aldazine
Absorption
60%
Aldazine
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Aldazine
Patient Information
Aldazine
Organisms Affected
Humans and other mammals