Thioridazine Hydrochloride
Brand names,
Thioridazine Hydrochloride
Analogs
Thioridazine Hydrochloride
Brand Names Mixture
Thioridazine Hydrochloride
Chemical_Formula
C21H26N2S2
Thioridazine Hydrochloride
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Thioridazine Hydrochloride
fda sheet
Thioridazine Hydrochloride
msds (material safety sheet)
Thioridazine Hydrochloride
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Thioridazine Hydrochloride
Molecular Weight
370.577 g/mol
Thioridazine Hydrochloride
Melting Point
73 oC
Thioridazine Hydrochloride
H2O Solubility
0.0336 mg/L
Thioridazine Hydrochloride
State
Solid
Thioridazine Hydrochloride
LogP
6.552
Thioridazine Hydrochloride
Dosage Forms
Suspension; Tablet
Thioridazine Hydrochloride
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Thioridazine Hydrochloride
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Thioridazine Hydrochloride
Absorption
60%
Thioridazine Hydrochloride
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Thioridazine Hydrochloride
Patient Information
Thioridazine Hydrochloride
Organisms Affected
Humans and other mammals