Orsanil
Brand names,
Orsanil
Analogs
Orsanil
Brand Names Mixture
Orsanil
Chemical_Formula
C21H26N2S2
Orsanil
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Orsanil
fda sheet
Orsanil
msds (material safety sheet)
Orsanil
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Orsanil
Molecular Weight
370.577 g/mol
Orsanil
Melting Point
73 oC
Orsanil
H2O Solubility
0.0336 mg/L
Orsanil
State
Solid
Orsanil
LogP
6.552
Orsanil
Dosage Forms
Suspension; Tablet
Orsanil
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Orsanil
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Orsanil
Absorption
60%
Orsanil
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Orsanil
Patient Information
Orsanil
Organisms Affected
Humans and other mammals