Thioridazine, Prolongatum
Brand names,
Thioridazine, Prolongatum
Analogs
Thioridazine, Prolongatum
Brand Names Mixture
Thioridazine, Prolongatum
Chemical_Formula
C21H26N2S2
Thioridazine, Prolongatum
RX_link
http://www.rxlist.com/cgi/generic3/thioridazine.htm
Thioridazine, Prolongatum
fda sheet
Thioridazine, Prolongatum
msds (material safety sheet)
Thioridazine, Prolongatum
Synthesis Reference
Bourquin et al., Helv. Chim. Acta 41, 1072 (1958)
Thioridazine, Prolongatum
Molecular Weight
370.577 g/mol
Thioridazine, Prolongatum
Melting Point
73 oC
Thioridazine, Prolongatum
H2O Solubility
0.0336 mg/L
Thioridazine, Prolongatum
State
Solid
Thioridazine, Prolongatum
LogP
6.552
Thioridazine, Prolongatum
Dosage Forms
Suspension; Tablet
Thioridazine, Prolongatum
Indication
For the treatment of schizophrenia and generalized anxiety disorder.
Thioridazine, Prolongatum
Pharmacology
Thioridazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Thioridazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Thioridazine, Prolongatum
Absorption
60%
Thioridazine, Prolongatum
side effects and Toxicity
LD50=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
Thioridazine, Prolongatum
Patient Information
Thioridazine, Prolongatum
Organisms Affected
Humans and other mammals