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Sertofran Brand names, Sertofran Analogs

Sertofran Brand Names Mixture

  • No information avaliable

Sertofran Chemical_Formula


Sertofran RX_link

Sertofran fda sheet

Sertofran FDA

Sertofran msds (material safety sheet)

Sertofran MSDS

Sertofran Synthesis Reference

No information avaliable

Sertofran Molecular Weight

266.381 g/mol

Sertofran Melting Point

214-218 oC

Sertofran H2O Solubility

No information avaliable

Sertofran State


Sertofran LogP


Sertofran Dosage Forms


Sertofran Indication

For relief of symptoms in various depressive syndromes, especially endogenous depression.

Sertofran Pharmacology

Desipramine, a tertiary amine tricyclic antidepressant, is structurally related to both the skeletal muscle relaxant cyclobenzaprine and the thioxanthene antipsychotics such as thiothixene. Desipramine is used to treat depression, pain of neuropathic origin, attention_deficit hyperactivity disorder, functional enuresis in children, panic and phobic disorder, and to manage some eating disorders. Desipramine inhibits the re-uptake of noradrenaline at the noradrenergic nerve endings and the re-uptake of serotonin (5-hydroxy tryptamine) at the serotoninergic nerve endings in the central nervous system. These two effects are considered to be the likely base of the antidepressant effect of Desipramine. The drug also has a strong anticholinergic effect and serves as an antagonist on a1 and H1 receptors.

Sertofran Absorption

Desipramine hydrochloride is rapidly and almost completely absorbed from the gastrointestinal tract. 90.5% (range 73-92%) of desipramine binds to plasma proteins.

Sertofran side effects and Toxicity

Male mice: LD50 = 290 mg/kg, female rats: LD50 = 320 mg/kg

Sertofran Patient Information

No information avaliable

Sertofran Organisms Affected

Humans and other mammals