Prysoline
Brand names,
Prysoline
Analogs
Prysoline
Brand Names Mixture
Prysoline
Chemical_Formula
C12H14N2O2
Prysoline
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Prysoline
fda sheet
Prysoline
msds (material safety sheet)
Prysoline
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Prysoline
Molecular Weight
218.252 g/mol
Prysoline
Melting Point
281.5 oC
Prysoline
H2O Solubility
500 mg/L
Prysoline
State
Solid
Prysoline
LogP
1.713
Prysoline
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Prysoline
Indication
For the treatment of epilepsy
Prysoline
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Prysoline
Absorption
90 to 100%
Prysoline
side effects and Toxicity
No information avaliable
Prysoline
Patient Information
Prysoline
Organisms Affected
Humans and other mammals