Midone
Brand names,
Midone
Analogs
Midone
Brand Names Mixture
Midone
Chemical_Formula
C12H14N2O2
Midone
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Midone
fda sheet
Midone
msds (material safety sheet)
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Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Midone
Molecular Weight
218.252 g/mol
Midone
Melting Point
281.5 oC
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H2O Solubility
500 mg/L
Midone
State
Solid
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LogP
1.713
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Dosage Forms
Tablet; Chewable tablets; Oral suspension
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Indication
For the treatment of epilepsy
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Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Midone
Absorption
90 to 100%
Midone
side effects and Toxicity
No information avaliable
Midone
Patient Information
Midone
Organisms Affected
Humans and other mammals