Lepsiral
Brand names,
Lepsiral
Analogs
Lepsiral
Brand Names Mixture
Lepsiral
Chemical_Formula
C12H14N2O2
Lepsiral
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Lepsiral
fda sheet
Lepsiral
msds (material safety sheet)
Lepsiral
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Lepsiral
Molecular Weight
218.252 g/mol
Lepsiral
Melting Point
281.5 oC
Lepsiral
H2O Solubility
500 mg/L
Lepsiral
State
Solid
Lepsiral
LogP
1.713
Lepsiral
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Lepsiral
Indication
For the treatment of epilepsy
Lepsiral
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Lepsiral
Absorption
90 to 100%
Lepsiral
side effects and Toxicity
No information avaliable
Lepsiral
Patient Information
Lepsiral
Organisms Affected
Humans and other mammals