Primacione
Brand names,
Primacione
Analogs
Primacione
Brand Names Mixture
Primacione
Chemical_Formula
C12H14N2O2
Primacione
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Primacione
fda sheet
Primacione
msds (material safety sheet)
Primacione
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Primacione
Molecular Weight
218.252 g/mol
Primacione
Melting Point
281.5 oC
Primacione
H2O Solubility
500 mg/L
Primacione
State
Solid
Primacione
LogP
1.713
Primacione
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Primacione
Indication
For the treatment of epilepsy
Primacione
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Primacione
Absorption
90 to 100%
Primacione
side effects and Toxicity
No information avaliable
Primacione
Patient Information
Primacione
Organisms Affected
Humans and other mammals