Primidon
Brand names,
Primidon
Analogs
Primidon
Brand Names Mixture
Primidon
Chemical_Formula
C12H14N2O2
Primidon
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Primidon
fda sheet
Primidon
msds (material safety sheet)
Primidon
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Primidon
Molecular Weight
218.252 g/mol
Primidon
Melting Point
281.5 oC
Primidon
H2O Solubility
500 mg/L
Primidon
State
Solid
Primidon
LogP
1.713
Primidon
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Primidon
Indication
For the treatment of epilepsy
Primidon
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Primidon
Absorption
90 to 100%
Primidon
side effects and Toxicity
No information avaliable
Primidon
Patient Information
Primidon
Organisms Affected
Humans and other mammals