Pms Primidone
Brand names,
Pms Primidone
Analogs
Pms Primidone
Brand Names Mixture
Pms Primidone
Chemical_Formula
C12H14N2O2
Pms Primidone
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Pms Primidone
fda sheet
Pms Primidone
msds (material safety sheet)
Pms Primidone
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Pms Primidone
Molecular Weight
218.252 g/mol
Pms Primidone
Melting Point
281.5 oC
Pms Primidone
H2O Solubility
500 mg/L
Pms Primidone
State
Solid
Pms Primidone
LogP
1.713
Pms Primidone
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Pms Primidone
Indication
For the treatment of epilepsy
Pms Primidone
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Pms Primidone
Absorption
90 to 100%
Pms Primidone
side effects and Toxicity
No information avaliable
Pms Primidone
Patient Information
Pms Primidone
Organisms Affected
Humans and other mammals