Milepsin
Brand names,
Milepsin
Analogs
Milepsin
Brand Names Mixture
Milepsin
Chemical_Formula
C12H14N2O2
Milepsin
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Milepsin
fda sheet
Milepsin
msds (material safety sheet)
Milepsin
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Milepsin
Molecular Weight
218.252 g/mol
Milepsin
Melting Point
281.5 oC
Milepsin
H2O Solubility
500 mg/L
Milepsin
State
Solid
Milepsin
LogP
1.713
Milepsin
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Milepsin
Indication
For the treatment of epilepsy
Milepsin
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Milepsin
Absorption
90 to 100%
Milepsin
side effects and Toxicity
No information avaliable
Milepsin
Patient Information
Milepsin
Organisms Affected
Humans and other mammals