Primacone
Brand names,
Primacone
Analogs
Primacone
Brand Names Mixture
Primacone
Chemical_Formula
C12H14N2O2
Primacone
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Primacone
fda sheet
Primacone
msds (material safety sheet)
Primacone
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Primacone
Molecular Weight
218.252 g/mol
Primacone
Melting Point
281.5 oC
Primacone
H2O Solubility
500 mg/L
Primacone
State
Solid
Primacone
LogP
1.713
Primacone
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Primacone
Indication
For the treatment of epilepsy
Primacone
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Primacone
Absorption
90 to 100%
Primacone
side effects and Toxicity
No information avaliable
Primacone
Patient Information
Primacone
Organisms Affected
Humans and other mammals