Primoline
Brand names,
Primoline
Analogs
Primoline
Brand Names Mixture
Primoline
Chemical_Formula
C12H14N2O2
Primoline
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Primoline
fda sheet
Primoline
msds (material safety sheet)
Primoline
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Primoline
Molecular Weight
218.252 g/mol
Primoline
Melting Point
281.5 oC
Primoline
H2O Solubility
500 mg/L
Primoline
State
Solid
Primoline
LogP
1.713
Primoline
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Primoline
Indication
For the treatment of epilepsy
Primoline
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Primoline
Absorption
90 to 100%
Primoline
side effects and Toxicity
No information avaliable
Primoline
Patient Information
Primoline
Organisms Affected
Humans and other mammals