Primaclone
Brand names,
Primaclone
Analogs
Primaclone
Brand Names Mixture
Primaclone
Chemical_Formula
C12H14N2O2
Primaclone
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Primaclone
fda sheet
Primaclone
msds (material safety sheet)
Primaclone
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Primaclone
Molecular Weight
218.252 g/mol
Primaclone
Melting Point
281.5 oC
Primaclone
H2O Solubility
500 mg/L
Primaclone
State
Solid
Primaclone
LogP
1.713
Primaclone
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Primaclone
Indication
For the treatment of epilepsy
Primaclone
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Primaclone
Absorption
90 to 100%
Primaclone
side effects and Toxicity
No information avaliable
Primaclone
Patient Information
Primaclone
Organisms Affected
Humans and other mammals