Sertan
Brand names,
Sertan
Analogs
Sertan
Brand Names Mixture
Sertan
Chemical_Formula
C12H14N2O2
Sertan
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Sertan
fda sheet
Sertan
msds (material safety sheet)
Sertan
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Sertan
Molecular Weight
218.252 g/mol
Sertan
Melting Point
281.5 oC
Sertan
H2O Solubility
500 mg/L
Sertan
State
Solid
Sertan
LogP
1.713
Sertan
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Sertan
Indication
For the treatment of epilepsy
Sertan
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Sertan
Absorption
90 to 100%
Sertan
side effects and Toxicity
No information avaliable
Sertan
Patient Information
Sertan
Organisms Affected
Humans and other mammals