Desoxyphenobarbitone
Brand names,
Desoxyphenobarbitone
Analogs
Desoxyphenobarbitone
Brand Names Mixture
Desoxyphenobarbitone
Chemical_Formula
C12H14N2O2
Desoxyphenobarbitone
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Desoxyphenobarbitone
fda sheet
Desoxyphenobarbitone
msds (material safety sheet)
Desoxyphenobarbitone
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Desoxyphenobarbitone
Molecular Weight
218.252 g/mol
Desoxyphenobarbitone
Melting Point
281.5 oC
Desoxyphenobarbitone
H2O Solubility
500 mg/L
Desoxyphenobarbitone
State
Solid
Desoxyphenobarbitone
LogP
1.713
Desoxyphenobarbitone
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Desoxyphenobarbitone
Indication
For the treatment of epilepsy
Desoxyphenobarbitone
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Desoxyphenobarbitone
Absorption
90 to 100%
Desoxyphenobarbitone
side effects and Toxicity
No information avaliable
Desoxyphenobarbitone
Patient Information
Desoxyphenobarbitone
Organisms Affected
Humans and other mammals