Apo-Primidone
Brand names,
Apo-Primidone
Analogs
Apo-Primidone
Brand Names Mixture
Apo-Primidone
Chemical_Formula
C12H14N2O2
Apo-Primidone
RX_link
http://www.rxlist.com/cgi/generic2/primid.htm
Apo-Primidone
fda sheet
Apo-Primidone
msds (material safety sheet)
Apo-Primidone
Synthesis Reference
Boon et al., Brit. pat. 666,027 (1952 to I.C.I.)
Apo-Primidone
Molecular Weight
218.252 g/mol
Apo-Primidone
Melting Point
281.5 oC
Apo-Primidone
H2O Solubility
500 mg/L
Apo-Primidone
State
Solid
Apo-Primidone
LogP
1.713
Apo-Primidone
Dosage Forms
Tablet; Chewable tablets; Oral suspension
Apo-Primidone
Indication
For the treatment of epilepsy
Apo-Primidone
Pharmacology
Primidone is a barbiturate with anticonvulsant properties. Primidone, either alone or used concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone raises electro- or chemoshock seizure thresholds or alters seizure patterns in experimental animals. Primidone per se has anticonvulsant activity as do its two metabolites, phenobarbital and phenylethylmalonamide (PEMA). In addition to its anticonvulsant activity, Primidone potentiates that of phenobarbital in experimental animals.
Apo-Primidone
Absorption
90 to 100%
Apo-Primidone
side effects and Toxicity
No information avaliable
Apo-Primidone
Patient Information
Apo-Primidone
Organisms Affected
Humans and other mammals