Methylphenidate hydrochloride
Methylphenidate hydrochloride Brand names, Methylphenidate hydrochloride Analogs
- 4311/B Ciba
- Calocain
- Centedein
- Centedrin
- Centedrine
- Centredin
- Concerta
- Focalin
- Focalin XR
- Methylphen
- Meridil
- Metadate
- Metadate CD
- Metadate ER
- Methyl phenidyl acetate
- Methylin
- Methylin ER
- Methylofenidan
- Methylphenidan
- Methylphenidate HCl
- Methylphenidate hydrochloride
- Methylphenidatum [Inn-Latin]
- Methylphenidylacetate hydrochloride
- Methypatch
- Metilfenidat hydrochloride
- Metilfenidato [Inn-Spanish]
- Metilfenidato [Italian]
- Phenidylate
- Plimasine
- PMS-Methylphenidate
- Riphenidate
- Ritalin
- Ritalin hydrochloride
- Ritalin LA
- Ritalin SR
- Ritalin-SR
- Ritaline
- Ritcher Works
Methylphenidate hydrochloride Brand Names Mixture
- No information avaliable
Methylphenidate hydrochloride Chemical_Formula
C14H19NO2
Methylphenidate hydrochloride RX_link
http://www.rxlist.com/cgi/generic/methphen.htm
Methylphenidate hydrochloride fda sheet
Methylphenidate hydrochloride msds (material safety sheet)
Methylphenidate hydrochloride Synthesis Reference
M. Hartmann, L. Panizzon, U.S. Pat. 2,507,631 (1950)
Methylphenidate hydrochloride Molecular Weight
233.306 g/mol
Methylphenidate hydrochloride Melting Point
224-226oC
Methylphenidate hydrochloride H2O Solubility
1255mg/L
Methylphenidate hydrochloride State
Solid
Methylphenidate hydrochloride LogP
3.192
Methylphenidate hydrochloride Dosage Forms
Tablets; Tablets (sustained release)
Methylphenidate hydrochloride Indication
For use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate-to-severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
Methylphenidate hydrochloride Pharmacology
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of dextroamphetamine.
Methylphenidate hydrochloride Absorption
Readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. Bioavailability is low (approximately 30%)
Methylphenidate hydrochloride side effects and Toxicity
Symptoms of overdose include vomiting, agitation, tremors, hyperreflexia, muscle twitching, convulsions (may be followed by coma), euphoria, confusion, hallucinations, delirium, sweating, flushing, headache, hyperpyrexia, tachycardia, palpitations, cardiac arrhythmias, hypertension, mydriasis, and dryness of mucous membranes. LD50=190mg/kg (orally in mice)
Methylphenidate hydrochloride Patient Information
Methylphenidate hydrochloride Organisms Affected
Humans and other mammals
