Methylin
Methylin Brand names, Methylin Analogs
- 4311/B Ciba
- Calocain
- Centedein
- Centedrin
- Centedrine
- Centredin
- Concerta
- Focalin
- Focalin XR
- Methylphen
- Meridil
- Metadate
- Metadate CD
- Metadate ER
- Methyl phenidyl acetate
- Methylin
- Methylin ER
- Methylofenidan
- Methylphenidan
- Methylphenidate HCl
- Methylphenidate hydrochloride
- Methylphenidatum [Inn-Latin]
- Methylphenidylacetate hydrochloride
- Methypatch
- Metilfenidat hydrochloride
- Metilfenidato [Inn-Spanish]
- Metilfenidato [Italian]
- Phenidylate
- Plimasine
- PMS-Methylphenidate
- Riphenidate
- Ritalin
- Ritalin hydrochloride
- Ritalin LA
- Ritalin SR
- Ritalin-SR
- Ritaline
- Ritcher Works
Methylin Brand Names Mixture
- No information avaliable
Methylin Chemical_Formula
C14H19NO2
Methylin RX_link
http://www.rxlist.com/cgi/generic/methphen.htm
Methylin fda sheet
Methylin msds (material safety sheet)
Methylin Synthesis Reference
M. Hartmann, L. Panizzon, U.S. Pat. 2,507,631 (1950)
Methylin Molecular Weight
233.306 g/mol
Methylin Melting Point
224-226oC
Methylin H2O Solubility
1255mg/L
Methylin State
Solid
Methylin LogP
3.192
Methylin Dosage Forms
Tablets; Tablets (sustained release)
Methylin Indication
For use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate-to-severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
Methylin Pharmacology
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of dextroamphetamine.
Methylin Absorption
Readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. Bioavailability is low (approximately 30%)
Methylin side effects and Toxicity
Symptoms of overdose include vomiting, agitation, tremors, hyperreflexia, muscle twitching, convulsions (may be followed by coma), euphoria, confusion, hallucinations, delirium, sweating, flushing, headache, hyperpyrexia, tachycardia, palpitations, cardiac arrhythmias, hypertension, mydriasis, and dryness of mucous membranes. LD50=190mg/kg (orally in mice)
Methylin Patient Information
Methylin Organisms Affected
Humans and other mammals
